Patient Testimonials

Patient Testimonial | Myanmar Patient | Successful Liver Transplant | Liver Damage | MGM Healthcare

Liver Transplant

17 Jan 2023

Dr Thiagarajan Srinivasan: Living Donor liver transplant

Liver Transplant

13 Jun 2022
Types of Liver Failure Diseases
Liver Transplant Treatments Procedures

Liver failure can be caused by various diseases and conditions, leading to different types of liver failure. Here are some of the main types:

1. Chronic Liver Failure:

  • Cirrhosis: This is a late stage of scarring (fibrosis) of the liver caused by many forms of liverdiseases and conditions, such as hepatitis and chronic alcoholism. Cirrhosis can eventually lead to liver failure.

2. Acute Liver Failure (ALF):

Hepatitis A, B, and C:

  • Viral infections affecting the liver can lead to acute liverfailure, especially in cases of severe or fulminant hepatitis.

Drug-Induced Liver Injury (DILI):

  • Certain medications, toxins, or herbal supplements can cause acute liver failure. Examples include acetaminophen overdose and reactions to some antibiotics.

Wilson's Disease:

  • A genetic disorder causing copper to accumulate in the liver, brain, and other organs. If not treated, it can lead to liver failure.

3. Alcoholic Liver Disease:

  • Alcoholic Hepatitis: Excessive and prolonged alcohol consumption can cause inflammation of the liver, leading to alcoholic hepatitis. This condition can progress to cirrhosis and liver failure.

4. Nonalcoholic Fatty Liver Disease (NAFLD):

  • Nonalcoholic Steatohepatitis (NASH): A more severe form of NAFLD, NASH involves inflammation and liver cell damage. If left untreated, it can progress to cirrhosis and liver failure.

5. Autoimmune Hepatitis:

  • Autoimmune Liver Disease: The immune system mistakenly attacks the liver, leading to inflammation and, in some cases, cirrhosis.

6. Genetic Liver Diseases:

Hemochromatosis:

  • An inherited disorder that causes the body to absorb and store too much iron, leading to liver damage.

Alpha-1 Antitrypsin Deficiency:

  • A genetic disorder that can cause liver disease, particularly in children.

Polycystic Liver Disease:

  • Inherited condition characterized by the growth of multiple cysts in the liver.

7. Metabolic Liver Diseases:

  • Wilson's Disease: Besides causing copper accumulation, Wilson's disease can also lead to liver failure.
  • Glycogen Storage Diseases: Genetic disorders affecting the storage and release of glycogen inthe liver can lead to liver damage.

8. Vascular Liver Diseases:

  • Budd-Chiari Syndrome: A rare condition where blood flow from the liver is obstructed, leading to liver damage and potentially liver failure.

Liver Cancer (Hepatocellular Carcinoma):

  • Advanced liver cancer can lead to liver failure. It may occur in the setting of chronic liver diseases such as cirrhosis.

1. Patient Evaluation:

  • Before undergoing a liver transplant, potential recipients undergo a thorough evaluation to assess their overall health, the severity of liver disease, and any other medical conditions.
  • This evaluation includes blood tests, imaging studies, and other diagnostic tests to determine the suitability of the patient for transplantation.

2. Listing and Waiting for a Donor:

  • This evaluation includes blood tests, imaging studies, and other diagnostic tests to determine the suitability of the patient for transplantation.
  • The allocation of donor organs is based on factors such as blood type, severity of illness, and geographic location.

3. Deceased Donor Transplant:

  • When a suitable donor becomes available, the transplant surgery is scheduled.
  • The recipient is prepared for surgery, and the diseased liver is removed during the transplantation procedure.
  • The healthy liver from the deceased donor is then implanted, and the blood vessels and bile ducts are carefully connected to ensure proper blood flow and drainage.

4. Living Donor Transplant:

  • In cases of living donor transplantation, a healthy individual donates a portion of their liver to the recipient.
  • Both the donor and recipient undergo separate surgeries simultaneously or in close succession.
  • The partial liver from the living donor is transplanted into the recipient, and both the donor's and recipient's livers have the capacity to regenerate.

5. Post-Transplant Care:

  • After surgery, recipients are closely monitored in the hospital's intensive care unit (ICU) or transplant unit.
  • Immunosuppressive medications are prescribed to prevent the recipient's immune system from rejecting the new liver.
  • Regular follow-up appointments and monitoring continue after discharge.

6. Immunosuppression:

  • Recipients must take immunosuppressive medications for the rest of their lives to prevent rejection of the transplanted liver.
  • The dosage and type of immunosuppressive drugs may be adjusted over time based on the individual's response and any side effects.

7. Rehabilitation and Recovery:

  • Physical therapy and rehabilitation are essential components of the post-transplant recovery process.
  • Recipients may need time to regain strength and adjust to their new lifestyle

8. Long-Term Follow-Up:

  • Long-term follow-up care is crucial to monitor for any signs of rejection,complications, or other health issues.
  • Recipients typically continue to receive medical care from a transplant team for an extended period.
Book an Appointment now!
Types of Liver Failure Diseases

Liver failure can be caused by various diseases and conditions, leading to different types of liver failure. Here are some of the main types:

1. Chronic Liver Failure:

  • Cirrhosis: This is a late stage of scarring (fibrosis) of the liver caused by many forms of liverdiseases and conditions, such as hepatitis and chronic alcoholism. Cirrhosis can eventually lead to liver failure.

2. Acute Liver Failure (ALF):

Hepatitis A, B, and C:

  • Viral infections affecting the liver can lead to acute liverfailure, especially in cases of severe or fulminant hepatitis.

Drug-Induced Liver Injury (DILI):

  • Certain medications, toxins, or herbal supplements can cause acute liver failure. Examples include acetaminophen overdose and reactions to some antibiotics.

Wilson's Disease:

  • A genetic disorder causing copper to accumulate in the liver, brain, and other organs. If not treated, it can lead to liver failure.

3. Alcoholic Liver Disease:

  • Alcoholic Hepatitis: Excessive and prolonged alcohol consumption can cause inflammation of the liver, leading to alcoholic hepatitis. This condition can progress to cirrhosis and liver failure.

4. Nonalcoholic Fatty Liver Disease (NAFLD):

  • Nonalcoholic Steatohepatitis (NASH): A more severe form of NAFLD, NASH involves inflammation and liver cell damage. If left untreated, it can progress to cirrhosis and liver failure.

5. Autoimmune Hepatitis:

  • Autoimmune Liver Disease: The immune system mistakenly attacks the liver, leading to inflammation and, in some cases, cirrhosis.

6. Genetic Liver Diseases:

Hemochromatosis:

  • An inherited disorder that causes the body to absorb and store too much iron, leading to liver damage.

Alpha-1 Antitrypsin Deficiency:

  • A genetic disorder that can cause liver disease, particularly in children.

Polycystic Liver Disease:

  • Inherited condition characterized by the growth of multiple cysts in the liver.

7. Metabolic Liver Diseases:

  • Wilson's Disease: Besides causing copper accumulation, Wilson's disease can also lead to liver failure.
  • Glycogen Storage Diseases: Genetic disorders affecting the storage and release of glycogen inthe liver can lead to liver damage.

8. Vascular Liver Diseases:

  • Budd-Chiari Syndrome: A rare condition where blood flow from the liver is obstructed, leading to liver damage and potentially liver failure.

Liver Cancer (Hepatocellular Carcinoma):

  • Advanced liver cancer can lead to liver failure. It may occur in the setting of chronic liver diseases such as cirrhosis.
Liver Transplant Treatments Procedures

1. Patient Evaluation:

  • Before undergoing a liver transplant, potential recipients undergo a thorough evaluation to assess their overall health, the severity of liver disease, and any other medical conditions.
  • This evaluation includes blood tests, imaging studies, and other diagnostic tests to determine the suitability of the patient for transplantation.

2. Listing and Waiting for a Donor:

  • This evaluation includes blood tests, imaging studies, and other diagnostic tests to determine the suitability of the patient for transplantation.
  • The allocation of donor organs is based on factors such as blood type, severity of illness, and geographic location.

3. Deceased Donor Transplant:

  • When a suitable donor becomes available, the transplant surgery is scheduled.
  • The recipient is prepared for surgery, and the diseased liver is removed during the transplantation procedure.
  • The healthy liver from the deceased donor is then implanted, and the blood vessels and bile ducts are carefully connected to ensure proper blood flow and drainage.

4. Living Donor Transplant:

  • In cases of living donor transplantation, a healthy individual donates a portion of their liver to the recipient.
  • Both the donor and recipient undergo separate surgeries simultaneously or in close succession.
  • The partial liver from the living donor is transplanted into the recipient, and both the donor's and recipient's livers have the capacity to regenerate.

5. Post-Transplant Care:

  • After surgery, recipients are closely monitored in the hospital's intensive care unit (ICU) or transplant unit.
  • Immunosuppressive medications are prescribed to prevent the recipient's immune system from rejecting the new liver.
  • Regular follow-up appointments and monitoring continue after discharge.

6. Immunosuppression:

  • Recipients must take immunosuppressive medications for the rest of their lives to prevent rejection of the transplanted liver.
  • The dosage and type of immunosuppressive drugs may be adjusted over time based on the individual's response and any side effects.

7. Rehabilitation and Recovery:

  • Physical therapy and rehabilitation are essential components of the post-transplant recovery process.
  • Recipients may need time to regain strength and adjust to their new lifestyle

8. Long-Term Follow-Up:

  • Long-term follow-up care is crucial to monitor for any signs of rejection,complications, or other health issues.
  • Recipients typically continue to receive medical care from a transplant team for an extended period.
Book an Appointment now!

Liver Failure Symptoms

Acute Liver Failure Symptoms:

  • 1. Jaundice: Yellowing of the skin and eyes due to the accumulation of bilirubin in the bloodstream.
  • 2. Abdominal Pain: Discomfort or pain in the upper right side of the abdomen, where the liver is located.
  • 3. Nausea and Vomiting: Feeling nauseous and vomiting may occur.
  • 4. Confusion: Mental confusion or changes in mental function.
  • 5. Fatigue: Extreme tiredness and weakness.
  • 6. Bleeding: Easy bruising, bleeding gums, or nosebleeds due to impaired blood clotting
  • 7. Swelling: Edema, or swelling in the legs and abdomen, may occur.

Chronic Liver Failure Symptoms:

  • 1. Fatigue: Persistent and severe tiredness.
  • 2. Weakness: Generalized weakness and lack of energy.
  • 3. Weight Loss: Unexplained weight loss may occur.
  • 4. Loss of Appetite: Decreased desire to eat.
  • 5. Jaundice: Yellowing of the skin and eyes.
  • 6. Swelling: Edema in the legs and abdomen due to fluid retention.
  • 7. Easy Bruising: Impaired blood clotting leading to easy bruising.
  • 8. Itching: Pruritus or itching of the skin.
  • 9. Dark Urine: Urine may appear dark in color.

Other Possible Symptoms:

  • 1. Ascites: Accumulation of fluid in the abdominal cavity, leading to abdominal swelling.
  • 2. Spider Angiomas: Small, spider-like blood vessels visible on the skin.
  • 3. Mental Changes: Confusion, difficulty concentrating, and personality changes.
  • 4. Gastrointestinal Bleeding: Vomiting blood or passing dark, tarry stools.
  • 5. Muscle Wasting: Loss of muscle mass and strength.
  • 6. Impotence: In men, erectile dysfunction may occur.
  • 7. Increased Sensitivity to Medications: The liver plays a role in metabolizing drugs, so liver failure can affect how medications are processed in the body.
Book an Appointment

Why choose MGM Liver Transplant India

Evaluation

Specialized Liver Transplant Team

Evaluation

Facilities and Infrastructure

Evaluation

Pre- and Post-Transplant Care

Evaluation

Location and Accessibility

Evaluation

Personalised and Comprehensive Care

Best Liver transplant Surgeons at MGM Healthcare, India

Evaluation

Senior Consultant & Director

Dr. Thiagarajan Srinivasan

Liver Diseases, Transplant & HPB Surgery

Know More Book an Appointment
Evaluation

Consultant

Dr Srikanth Thummala

Liver Diseases, Transplant & HPB Surgery

Know More Book an Appoinment
Evaluation

Consultant

Dr L SoundaraRajan

Liver Diseases, Transplant & HPB Surgery

Know More Book an Appoinment

FAQ’s

Liver transplantation is a surgical procedure in which a damaged or diseased liver is replaced with a healthy liver from a deceased or living donor.

Individuals with severe liver diseases, such as cirrhosis, liver failure, or certain genetic conditions, may require a liver transplant when other treatments are ineffective.

The success rate is generally high, with many recipients experiencing improved quality of life. Success depends on various factors, including the recipient's health and the availability of a suitable donor.

Living donors may face surgical risks, but with proper screening and medical care, the risks are minimized. The long-term impact on a donor's health is usually positive.